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A New CRB1 Rat Mutation Links Müller Glial Cells to Retinal Telangiectasia
(Society for Neuroscience, 2015-04)
Wehave identified and characterized a spontaneousBrownNorwayfrom Janvier rat strain (BN-J) presenting a progressive retinal degeneration
associated with early retinal telangiectasia, neuronal alterations, and loss of ...
Sphingolipids as critical players in retinal physiology and pathology
(American Society for Biochemistry and Molecular Biology, 2021-01)
Sphingolipids have emerged as bioactive lipids involved in the regulation of many physiological and pathological processes. In the retina, they have been established toparticipate in numerousprocesses, suchas neuronal ...
Metipranolol promotes structure and function of retinal photoreceptors in the rd10 mouse model of human retinitis pigmentosa
(Wiley Blackwell Publishing, Inc, 2019-01)
Metipranolol is a b-adrenergic receptor antagonist that is given orally for the treatment of hypertension and also applied topically to the cornea for treating glaucoma. It also inhibits nitrosative stress which has ...
Efectos de la luz sobre degeneración retinal. Concepto de contaminación luminicaLight effects on retinal degeneration: Light pollution concept
(Asociación Física Argentina, 2018-09)
La luz visible es captada por la retina, parte del sistema nervioso central, la cual procesa la información a través de sus células fotorreceptoras mediante el proceso denominado fototransducción. El resto de las células ...
Non-visual photopigments effects of constant light-emitting diode light exposure on the inner retina of Wistar rats
(Frontiers Media S.A., 2017-08)
The retina is part of the central nervous system specially adapted to capture light photons and transmit this information to the brain through photosensitive retinal cells involved in visual and non-visual activities. ...
Degeneración retinal, Retinitis Pigmentosa: generalidades, mutaciones en el mecanismo de fototransducción y modelo de investigación
(Universidad Nacional de Córdoba. Facultad de Ciencias Químicas, 2013-08)
La degeneración retinal (DR) es un proceso patológico que provoca muerte de célulasretinales, pérdida de estructura del tejido y finalmente ceguera. Retinitis pigmentosa (RP) comprende un grupo de distrofias retinales que ...
Superior cervical gangliectomy induces non-exudative age-related macular degeneration in mice
(Company of Biologists, 2018-02)
Non-exudative age-related macular degeneration, a prevalent cause of blindness, is a progressive and degenerative disease characterized by alterations in Bruch’s membrane, retinal pigment epithelium, and photoreceptors ...
Druse-Induced Morphology Evolution in Retinal Pigment Epithelium
(Cornell University, 2016-09)
The retinal pigment epithelium (RPE) is a key site of pathogenesis for many retina diseases. The formation of drusen in the retina is characteristic of retinal degeneration. We investigate morphological changes in the RPE ...
Non-Exudative Age-Related Macular Degeneration: New Experimental Insights
(Nova Science Publishers, 2020)
Non-exudativeage-related macular degeneration (NE-AMD), the main cause of blindness in theelderly, is a condition involving progressive atrophy of the retinal pigment epitheliumand photoreceptors exclusively localized at ...
Oxidative stress in retinal degeneration promoted by constant LED light
(Frontiers Media S.A., 2019-01)
Light pollution by artificial light, might accelerate retinal diseases and circadian asynchrony. The excess of light exposure is a growing problem in societies, so studies on the consequences of long-term exposure to low ...